(404) The request is not recognized during Ti compile

When attempting to build my Ti app, run it in the simulator, or run it on my device, suddenly I get this error during compile:

[ERROR] :  (404) The request is not recognized!
TRACE  | titanium exited with exit code 100
ERROR  | Error: ti run exited with error code 100
    at ChildProcess.<anonymous> (/Users/natej/.appcelerator/install/4.1.2/package/node_modules/appc-cli-titanium/plugins/run.js:84:66)
    at ChildProcess.emit (events.js:117:20)
    at Process.ChildProcess._handle.onexit (child_process.js:810:12)

I am running latest Appcelerator Studio and building with Ti SDK 4.1.0 GA. I have tried to Clean my project, but that didn't help. Normally when there's a bug in my code I get a helpful error message and it indicates the offending line number. But this tells me nothing and I have no idea what to do about it.

I did find this bug report: https://jira.appcelerator.org/browse/CLI-764

Anything I can do?